Click on the PubMed link to see a complete list of publications from the lab:

Below are a few selected publications.

Latency Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy

Pardons M, Fromentin R, Pagliuzza A,  Routy JP, Chomont N. Cell Reports. In press.

 

Infrequent HIV infection of circulating monocytes during antiretroviral therapy.

Massanella M, Bakeman W, Sithinamsuwan P, Fletcher JLK, Chomchey N, Tipsuk S, Chalermchai T, Routy JP, Ananworanich J, Valcour VG, Chomont N; SEARCH 011 Study Group. J Virol. 2019.

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

Pardons M, Baxter AE, Massanella M, Pagliuzza A, Fromentin R, Dufour C, Leyre L, Routy JP, Kaufmann DE, Chomont N. PLoS Pathog. 2019.

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals.

Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. Nat Commun. 2019.

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise. 

Plantin J, Massanella M, Chomont N. Retrovirology. 2018.

Residual inflammation and viral reservoirs: alliance against an HIV cure.

Massanella, M., R. Fromentin, and N. Chomont. Curr Opin HIV AIDS2016.

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.

Fromentin, R., W. Bakeman, M. B. Lawani, G. Khoury, W. Hartogensis, S. DaFonseca, M. Killian, L. Epling, R. Hoh, E. Sinclair, F. M. Hecht, P. Bacchetti, S. G. Deeks, S. R. Lewin, R. P. Sekaly, and N. Chomont. PLoS Pathog. 2016.

A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.

Procopio, F. A., R. Fromentin, D. A. Kulpa, J. H. Brehm, A. G. Bebin, M. C. Strain, D. D. Richman, U. O'Doherty, S. Palmer, F. M. Hecht, R. Hoh, R. J. Barnard, M. D. Miller, D. J. Hazuda, S. G. Deeks, R. P. Sekaly, and N. Chomont. EBioMedicine. 2015.

HIV persistence in the setting of antiretroviral therapy: when, where and how does HIV hide?

Kulpa, D. A., and N. Chomont. J Virus Erad. 2015.

Cross-clade ultrasensitive PCR-based assays to measure HIV persistence in large-cohort studies.

Vandergeeten, C., R. Fromentin, E. Merlini, M. B. Lawani, S. DaFonseca, W. Bakeman, A. McNulty, M. Ramgopal, N. Michael, J. H. Kim, J. Ananworanich, and N. Chomont. J Virol2014.

Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children.

Ananworanich, J., T. Puthanakit, P. Suntarattiwong, K. Chokephaibulkit, S. J. Kerr, R. Fromentin, W. Bakeman, J. Intasan, A. Mahanontharit, S. Sirivichayakul, N. Chomont, and H.-N. S. Group. AIDS. 2014.

Interleukin-7 promotes HIV persistence during antiretroviral therapy.

Vandergeeten, C., R. Fromentin, S. DaFonseca, M. B. Lawani, I. Sereti, M. M. Lederman, M. Ramgopal, J. P. Routy, R. P. Sekaly, and N. Chomont. Blood2013. 

The role of cytokines in the establishment, persistence and eradication of the HIV reservoir.

Vandergeeten, C., R. Fromentin, and N. Chomont. Cytokine Growth Factor Rev2012.

Finding a cure for HIV: will it ever be achievable?

Lewin, S. R., V. A. Evans, J. H. Elliott, B. Spire, and N. Chomont. J Int AIDS Soc2011.

Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV.

N. Chomont, S. DaFonseca, C. Vandergeeten, P. Ancuta, and R. P. Sekaly. Curr Opin HIV AIDS2011.

HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals.

Trono, D., C. Van Lint, C. Rouzioux, E. Verdin, F. Barre-Sinoussi, T. W. Chun, and N. Chomont. Science. 2010.

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

N. Chomont, M. El-Far, P. Ancuta, L. Trautmann, F. A. Procopio, B. Yassine-Diab, G. Boucher, M. R. Boulassel, G. Ghattas, J. M. Brenchley, T. W. Schacker, B. J. Hill, D. C. Douek, J. P. Routy, E. K. Haddad, and R. P. Sekaly. Nat Med. 2009.

  

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